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Mucuna pruriens and Its Major Constituent L-DOPA Recover Spermatogenic Loss by Combating ROS, Loss of Mitochondrial Membrane Potential and Apoptosis

Overview of attention for article published in PLOS ONE, January 2013
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Title
Mucuna pruriens and Its Major Constituent L-DOPA Recover Spermatogenic Loss by Combating ROS, Loss of Mitochondrial Membrane Potential and Apoptosis
Published in
PLOS ONE, January 2013
DOI 10.1371/journal.pone.0054655
Pubmed ID
Authors

Akhand Pratap Singh, Saumya Sarkar, Muktanand Tripathi, Singh Rajender

Abstract

The Ayurvedic medicinal system claims Mucuna pruriens (MP) to possess pro-male fertility, aphrodisiac and adaptogenic properties. Some scientific evidence also supports its pro-male fertility properties; however, the mechanism of its action is not yet clear. The present study aimed at demonstrating spermatogenic restorative efficacy of MP and its major constituent L-DOPA (LD), and finding the possible mechanism of action thereof in a rat model.

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Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
India 1 1%
Unknown 86 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 16%
Student > Ph. D. Student 13 15%
Student > Bachelor 11 13%
Student > Master 8 9%
Other 7 8%
Other 11 13%
Unknown 24 27%
Readers by discipline Count As %
Medicine and Dentistry 16 18%
Agricultural and Biological Sciences 14 16%
Biochemistry, Genetics and Molecular Biology 9 10%
Neuroscience 6 7%
Arts and Humanities 4 5%
Other 8 9%
Unknown 31 35%