Title |
Probiotic Bacteria Induce a ‘Glow of Health’
|
---|---|
Published in |
PLOS ONE, January 2013
|
DOI | 10.1371/journal.pone.0053867 |
Pubmed ID | |
Authors |
Tatiana Levkovich, Theofilos Poutahidis, Christopher Smillie, Bernard J. Varian, Yassin M. Ibrahim, Jessica R. Lakritz, Eric J. Alm, Susan E. Erdman |
Abstract |
Radiant skin and hair are universally recognized as indications of good health. However, this 'glow of health' display remains poorly understood. We found that feeding of probiotic bacteria to aged mice induced integumentary changes mimicking peak health and reproductive fitness characteristic of much younger animals. Eating probiotic yogurt triggered epithelial follicular anagen-phase shift with sebocytogenesis resulting in thick lustrous fur due to a bacteria-triggered interleukin-10-dependent mechanism. Aged male animals eating probiotics exhibited increased subcuticular folliculogenesis, when compared with matched controls, yielding luxuriant fur only in probiotic-fed subjects. Female animals displayed probiotic-induced hyperacidity coinciding with shinier hair, a feature that also aligns with fertility in human females. Together these data provide insights into mammalian evolution and novel strategies for integumentary health. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 13 | 25% |
United Kingdom | 7 | 13% |
Canada | 4 | 8% |
France | 1 | 2% |
Ireland | 1 | 2% |
Colombia | 1 | 2% |
Japan | 1 | 2% |
Unknown | 25 | 47% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 40 | 75% |
Scientists | 9 | 17% |
Practitioners (doctors, other healthcare professionals) | 3 | 6% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Germany | 2 | <1% |
Denmark | 2 | <1% |
Switzerland | 1 | <1% |
United Kingdom | 1 | <1% |
Hungary | 1 | <1% |
Canada | 1 | <1% |
Greece | 1 | <1% |
Russia | 1 | <1% |
Other | 0 | 0% |
Unknown | 259 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 49 | 18% |
Student > Ph. D. Student | 42 | 15% |
Student > Bachelor | 35 | 13% |
Student > Master | 29 | 11% |
Other | 21 | 8% |
Other | 45 | 17% |
Unknown | 50 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 71 | 26% |
Medicine and Dentistry | 46 | 17% |
Biochemistry, Genetics and Molecular Biology | 20 | 7% |
Immunology and Microbiology | 17 | 6% |
Chemistry | 10 | 4% |
Other | 42 | 15% |
Unknown | 65 | 24% |