| Title |
Immediate and Heterogeneous Response of the LiaFSR Two-Component System of Bacillus subtilis to the Peptide Antibiotic Bacitracin
|
|---|---|
| Published in |
PLOS ONE, January 2013
|
| DOI | 10.1371/journal.pone.0053457 |
| Pubmed ID | |
| Authors |
Sara Kesel, Andreas Mader, Carolin Höfler, Thorsten Mascher, Madeleine Leisner |
| Abstract |
Two-component signal transduction systems are one means of bacteria to respond to external stimuli. The LiaFSR two-component system of Bacillus subtilis consists of a regular two-component system LiaRS comprising the core Histidine Kinase (HK) LiaS and the Response Regulator (RR) LiaR and additionally the accessory protein LiaF, which acts as a negative regulator of LiaRS-dependent signal transduction. The complete LiaFSR system was shown to respond to various peptide antibiotics interfering with cell wall biosynthesis, including bacitracin. |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| United Kingdom | 1 | 2% |
| Canada | 1 | 2% |
| Denmark | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 49 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 39% |
| Student > Bachelor | 8 | 15% |
| Researcher | 6 | 11% |
| Student > Master | 4 | 7% |
| Student > Doctoral Student | 3 | 6% |
| Other | 3 | 6% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 54% |
| Biochemistry, Genetics and Molecular Biology | 10 | 19% |
| Immunology and Microbiology | 3 | 6% |
| Computer Science | 1 | 2% |
| Unspecified | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 8 | 15% |