| Title |
Single-Cell and Population NF-κB Dynamic Responses Depend on Lipopolysaccharide Preparation
|
|---|---|
| Published in |
PLOS ONE, January 2013
|
| DOI | 10.1371/journal.pone.0053222 |
| Pubmed ID | |
| Authors |
Miriam V. Gutschow, Jacob J. Hughey, Nicholas A. Ruggero, Bryce T. Bajar, Sean D. Valle, Markus W. Covert |
| Abstract |
Lipopolysaccharide (LPS), found in the outer membrane of gram-negative bacteria, elicits a strong response from the transcription factor family Nuclear factor (NF)-κB via Toll-like receptor (TLR) 4. The cellular response to lipopolysaccharide varies depending on the source and preparation of the ligand, however. Our goal was to compare single-cell NF-κB dynamics across multiple sources and concentrations of LPS. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 2% |
| Ireland | 1 | 2% |
| Switzerland | 1 | 2% |
| Unknown | 61 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 36% |
| Researcher | 10 | 16% |
| Student > Master | 7 | 11% |
| Student > Bachelor | 6 | 9% |
| Student > Doctoral Student | 4 | 6% |
| Other | 8 | 13% |
| Unknown | 6 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 52% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Engineering | 7 | 11% |
| Computer Science | 3 | 5% |
| Chemistry | 3 | 5% |
| Other | 4 | 6% |
| Unknown | 6 | 9% |