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Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects

Overview of attention for article published in PLOS ONE, December 2012
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Title
Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects
Published in
PLOS ONE, December 2012
DOI 10.1371/journal.pone.0052774
Pubmed ID
Authors

Gloria Formoso, Merilda Taraborrelli, Maria T. Guagnano, Monica D’Adamo, Natalia Di Pietro, Armando Tartaro, Agostino Consoli

Abstract

Obesity is characterized by a low grade chronic inflammation state. Indeed circulating pro-inflammatory cytokines, such as TNF-α and IL-6, are elevated in obese subjects, while anti-inflammatory cytokines, such as IL-10, appear to be reduced. Cytokines profile improves after weight loss, but how visceral or subcutaneous fat loss respectively affect pro- or anti-inflammatory cytokines plasma levels has not been precisely assessed. Therefore in the present study we correlated changes in circulating cytokine profile with quantitative changes in visceral and subcutaneous adipose tissue depots measured by an ad hoc Magnetic Resonance Imaging (MRI) protocol before and after weight loss.

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Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 66 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 20%
Researcher 12 18%
Student > Bachelor 9 14%
Student > Ph. D. Student 7 11%
Student > Postgraduate 4 6%
Other 6 9%
Unknown 15 23%
Readers by discipline Count As %
Medicine and Dentistry 15 23%
Agricultural and Biological Sciences 8 12%
Immunology and Microbiology 6 9%
Biochemistry, Genetics and Molecular Biology 6 9%
Nursing and Health Professions 3 5%
Other 10 15%
Unknown 18 27%