Title |
Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus in the United States: A Meta-Analysis
|
---|---|
Published in |
PLOS ONE, January 2013
|
DOI | 10.1371/journal.pone.0052722 |
Pubmed ID | |
Authors |
Vanja M. Dukic, Diane S. Lauderdale, Jocelyn Wilder, Robert S. Daum, Michael Z. David |
Abstract |
Staphylococcus aureus is the most frequent cause of skin and soft tissue infections in humans. Methicillin-resistant strains of S. aureus (MRSA) that emerged in the 1960s presented a relatively limited public health threat until the 1990s, when novel community-associated (CA-) MRSA strains began circulating. CA-MRSA infections are now common, resulting in serious and sometimes fatal infections in otherwise healthy people. Although some have suggested that there is an epidemic of CA-MRSA in the U.S., the origins, extent, and geographic variability of CA-MRSA infections are not known. We present a meta-analysis of published studies that included trend data from a single site or region, and derive summary epidemic curves of CA-MRSA spread over time. Our analysis reveals a dramatic increase in infections over the past two decades, with CA-MRSA strains now endemic at unprecedented levels in many US regions. This increase has not been geographically homogeneous, and appears to have occurred earlier in children than adults. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 60% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | <1% |
India | 1 | <1% |
Denmark | 1 | <1% |
Nigeria | 1 | <1% |
United States | 1 | <1% |
Unknown | 99 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 19 | 18% |
Researcher | 17 | 16% |
Student > Ph. D. Student | 16 | 15% |
Student > Bachelor | 8 | 8% |
Student > Postgraduate | 6 | 6% |
Other | 17 | 16% |
Unknown | 21 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 24% |
Agricultural and Biological Sciences | 21 | 20% |
Biochemistry, Genetics and Molecular Biology | 10 | 10% |
Immunology and Microbiology | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Other | 16 | 15% |
Unknown | 25 | 24% |