| Title |
Elevated Plasma Angiopoietin-2 Levels and Primary Graft Dysfunction after Lung Transplantation
|
|---|---|
| Published in |
PLOS ONE, December 2012
|
| DOI | 10.1371/journal.pone.0051932 |
| Pubmed ID | |
| Authors |
Joshua M. Diamond, Mary K. Porteous, Edward Cantu, Nuala J. Meyer, Rupal J. Shah, David J. Lederer, Steven M. Kawut, James Lee, Scarlett L. Bellamy, Scott M. Palmer, Vibha N. Lama, Sangeeta M. Bhorade, Maria Crespo, Ejigayehu Demissie, Keith Wille, Jonathan Orens, Pali D. Shah, Ann Weinacker, David Weill, Selim Arcasoy, David S. Wilkes, Lorraine B. Ware, Jason D. Christie |
| Abstract |
Primary graft dysfunction (PGD) is a significant contributor to early morbidity and mortality after lung transplantation. Increased vascular permeability in the allograft has been identified as a possible mechanism leading to PGD. Angiopoietin-2 serves as a partial antagonist to the Tie-2 receptor and induces increased endothelial permeability. We hypothesized that elevated Ang2 levels would be associated with development of PGD. |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | 4% |
| Spain | 1 | 4% |
| Turkey | 1 | 4% |
| Netherlands | 1 | 4% |
| Unknown | 19 | 83% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 17% |
| Student > Postgraduate | 3 | 13% |
| Professor > Associate Professor | 3 | 13% |
| Lecturer | 2 | 9% |
| Other | 2 | 9% |
| Other | 6 | 26% |
| Unknown | 3 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 52% |
| Agricultural and Biological Sciences | 2 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Social Sciences | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 5 | 22% |