Title |
Quercetin Potentiates Doxorubicin Mediated Antitumor Effects against Liver Cancer through p53/Bcl-xl
|
---|---|
Published in |
PLOS ONE, December 2012
|
DOI | 10.1371/journal.pone.0051764 |
Pubmed ID | |
Authors |
Guanyu Wang, Jiawei Zhang, Luying Liu, Sherven Sharma, Qinghua Dong |
Abstract |
The dose-dependent toxicities of doxorubicin (DOX) limit its clinical applications, particularly in drug-resistant cancers, such as liver cancer. In this study, we investigated the role of quercetin on the antitumor effects of DOX on liver cancer cells and its ability to provide protection against DOX-mediated liver damage in mice. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Lebanon | 1 | 1% |
Canada | 1 | 1% |
Unknown | 84 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 16% |
Student > Bachelor | 12 | 14% |
Student > Master | 11 | 13% |
Researcher | 8 | 9% |
Student > Doctoral Student | 5 | 6% |
Other | 13 | 15% |
Unknown | 23 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 14 | 16% |
Biochemistry, Genetics and Molecular Biology | 11 | 13% |
Medicine and Dentistry | 10 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 9% |
Chemistry | 7 | 8% |
Other | 6 | 7% |
Unknown | 30 | 35% |