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Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice

Overview of attention for article published in PLOS ONE, December 2012
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Title
Prophylactic Valproic Acid Treatment Prevents Schizophrenia-Related Behaviour in Disc1-L100P Mutant Mice
Published in
PLOS ONE, December 2012
DOI 10.1371/journal.pone.0051562
Pubmed ID
Authors

Tatiana V. Lipina, Fahmida Nipa Haque, Alexander McGirr, Paul C. Boutros, Thorsten Berger, Tak W. Mak, John C. Roder, Albert H. C. Wong

Abstract

Schizophrenia is a neurodevelopmental disorder with onset early in adulthood. Disrupted-In-Schizophrenia-1 (DISC1) is a susceptibility gene for schizophrenia and other psychiatric disorders. Disc1-L100P mutant mice show behaviors relevant to schizophrenia at 12 weeks, but not at 8 weeks of age, and may be useful for investigating the onset of schizophrenia in early adulthood.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 20%
Student > Master 7 18%
Student > Bachelor 6 15%
Student > Doctoral Student 4 10%
Researcher 4 10%
Other 6 15%
Unknown 5 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 28%
Neuroscience 9 23%
Medicine and Dentistry 6 15%
Biochemistry, Genetics and Molecular Biology 3 8%
Psychology 2 5%
Other 3 8%
Unknown 6 15%