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Use of NHANES Data to Link Chemical Exposures to Chronic Diseases: A Cautionary Tale

Overview of attention for article published in PLOS ONE, December 2012
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Title
Use of NHANES Data to Link Chemical Exposures to Chronic Diseases: A Cautionary Tale
Published in
PLOS ONE, December 2012
DOI 10.1371/journal.pone.0051086
Pubmed ID
Authors

Judy S. LaKind, Michael Goodman, Daniel Q. Naiman

Abstract

The National Health and Nutrition Examination Survey (NHANES) is one example of cross-sectional datasets that have been used to draw causal inferences regarding environmental chemical exposures and adverse health outcomes. Our objectives were to analyze four NHANES datasets using consistent a priori selected methods to address the following questions: Is there a consistent association between urinary bisphenol A (BPA) measures and diabetes, coronary heart disease (CHD), and/or heart attack across surveys? Is NHANES an appropriate dataset for investigating associations between chemicals with short physiologic half-lives such as BPA and chronic diseases with multi-factorial etiologies? Data on urinary BPA and health outcomes from 2003-2004, 2005-2006, 2007-2008, and 2009-2010 were available.

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Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Thailand 1 <1%
Unknown 106 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 15%
Researcher 14 13%
Student > Master 11 10%
Student > Bachelor 11 10%
Student > Doctoral Student 7 6%
Other 27 25%
Unknown 22 20%
Readers by discipline Count As %
Medicine and Dentistry 24 22%
Biochemistry, Genetics and Molecular Biology 15 14%
Agricultural and Biological Sciences 10 9%
Environmental Science 8 7%
Social Sciences 5 5%
Other 23 21%
Unknown 23 21%