| Title |
Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection
|
|---|---|
| Published in |
PLOS ONE, November 2012
|
| DOI | 10.1371/journal.pone.0050667 |
| Pubmed ID | |
| Authors |
Yuri Souwer, Alexander Griekspoor, Jelle de Wit, Chiara Martinoli, Elena Zagato, Hans Janssen, Tineke Jorritsma, Yotam E. Bar-Ephraïm, Maria Rescigno, Jacques Neefjes, S. Marieke van Ham |
| Abstract |
The bacterial pathogen Salmonella causes worldwide disease. A major route of intestinal entry involves M cells, providing access to B cell-rich Peyer's Patches. Primary human B cells phagocytose Salmonella typhimurium upon recognition by the specific surface Ig receptor (BCR). As it is unclear how Salmonella disseminates systemically, we studied whether Salmonella can use B cells as a transport device for spreading. |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Netherlands | 1 | 2% |
| Unknown | 56 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 28% |
| Researcher | 13 | 22% |
| Student > Master | 10 | 17% |
| Student > Bachelor | 3 | 5% |
| Professor > Associate Professor | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 8 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 40% |
| Immunology and Microbiology | 14 | 24% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Unspecified | 2 | 3% |
| Medicine and Dentistry | 2 | 3% |
| Other | 5 | 9% |
| Unknown | 8 | 14% |