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Parental Diabetes: The Akita Mouse as a Model of the Effects of Maternal and Paternal Hyperglycemia in Wildtype Offspring

Overview of attention for article published in PLOS ONE, November 2012
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Title
Parental Diabetes: The Akita Mouse as a Model of the Effects of Maternal and Paternal Hyperglycemia in Wildtype Offspring
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0050210
Pubmed ID
Authors

Corinna Grasemann, Maureen J. Devlin, Paulina A. Rzeczkowska, Ralf Herrmann, Bernhard Horsthemke, Berthold P. Hauffa, Marc Grynpas, Christina Alm, Mary L. Bouxsein, Mark R. Palmert

Abstract

Maternal diabetes and high-fat feeding during pregnancy have been linked to later life outcomes in offspring. To investigate the effects of both maternal and paternal hyperglycemia on offspring phenotypes, we utilized an autosomal dominant mouse model of diabetes (hypoinsulinemic hyperglycemia in Akita mice). We determined metabolic and skeletal phenotypes in wildtype offspring of Akita mothers and fathers.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 29%
Researcher 5 14%
Student > Bachelor 4 11%
Student > Master 3 9%
Student > Doctoral Student 1 3%
Other 6 17%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 31%
Biochemistry, Genetics and Molecular Biology 8 23%
Medicine and Dentistry 6 17%
Business, Management and Accounting 1 3%
Nursing and Health Professions 1 3%
Other 1 3%
Unknown 7 20%