Title |
Parental Diabetes: The Akita Mouse as a Model of the Effects of Maternal and Paternal Hyperglycemia in Wildtype Offspring
|
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Published in |
PLOS ONE, November 2012
|
DOI | 10.1371/journal.pone.0050210 |
Pubmed ID | |
Authors |
Corinna Grasemann, Maureen J. Devlin, Paulina A. Rzeczkowska, Ralf Herrmann, Bernhard Horsthemke, Berthold P. Hauffa, Marc Grynpas, Christina Alm, Mary L. Bouxsein, Mark R. Palmert |
Abstract |
Maternal diabetes and high-fat feeding during pregnancy have been linked to later life outcomes in offspring. To investigate the effects of both maternal and paternal hyperglycemia on offspring phenotypes, we utilized an autosomal dominant mouse model of diabetes (hypoinsulinemic hyperglycemia in Akita mice). We determined metabolic and skeletal phenotypes in wildtype offspring of Akita mothers and fathers. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
Unknown | 34 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 29% |
Researcher | 5 | 14% |
Student > Bachelor | 4 | 11% |
Student > Master | 3 | 9% |
Student > Doctoral Student | 1 | 3% |
Other | 6 | 17% |
Unknown | 6 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 31% |
Biochemistry, Genetics and Molecular Biology | 8 | 23% |
Medicine and Dentistry | 6 | 17% |
Business, Management and Accounting | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 1 | 3% |
Unknown | 7 | 20% |