| Title |
Lack of Bcr and Abr Promotes Hypoxia-Induced Pulmonary Hypertension in Mice
|
|---|---|
| Published in |
PLOS ONE, November 2012
|
| DOI | 10.1371/journal.pone.0049756 |
| Pubmed ID | |
| Authors |
Min Yu, Dapeng Gong, Min Lim, Anna Arutyunyan, John Groffen, Nora Heisterkamp |
| Abstract |
Bcr and Abr are GTPase activating proteins that specifically downregulate activity of the small GTPase Rac in restricted cell types in vivo. Rac1 is expressed in smooth muscle cells, a critical cell type involved in the pathogenesis of pulmonary hypertension. The molecular mechanisms that underlie hypoxia-associated pulmonary hypertension are not well-defined. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Peru | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 25 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 24% |
| Student > Ph. D. Student | 5 | 20% |
| Researcher | 4 | 16% |
| Professor > Associate Professor | 3 | 12% |
| Other | 3 | 12% |
| Other | 3 | 12% |
| Unknown | 1 | 4% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 32% |
| Medicine and Dentistry | 6 | 24% |
| Biochemistry, Genetics and Molecular Biology | 3 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Sports and Recreations | 1 | 4% |
| Other | 3 | 12% |
| Unknown | 3 | 12% |