| Title |
VLPs Displaying a Single L2 Epitope Induce Broadly Cross-Neutralizing Antibodies against Human Papillomavirus
|
|---|---|
| Published in |
PLOS ONE, November 2012
|
| DOI | 10.1371/journal.pone.0049751 |
| Pubmed ID | |
| Authors |
Ebenezer Tumban, Julianne Peabody, Mitchell Tyler, David S. Peabody, Bryce Chackerian |
| Abstract |
Virus-like Particles (VLPs) display can be used to increase the immunogenicity of heterologous antigens. Here, we report the use of a bacteriophage MS2-based VLP display platform to develop a monovalent vaccine targeting a broadly neutralizing epitope in the minor capsid protein human papillomavirus (HPV) that provides broad protection from diverse HPV types in a mouse pseudovirus infection model. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 1% |
| Unknown | 70 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 15% |
| Researcher | 11 | 15% |
| Student > Bachelor | 9 | 13% |
| Student > Doctoral Student | 7 | 10% |
| Student > Master | 6 | 8% |
| Other | 8 | 11% |
| Unknown | 19 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 21% |
| Biochemistry, Genetics and Molecular Biology | 12 | 17% |
| Immunology and Microbiology | 9 | 13% |
| Medicine and Dentistry | 9 | 13% |
| Chemistry | 3 | 4% |
| Other | 2 | 3% |
| Unknown | 21 | 30% |