| Title |
The ABCA1 Gene R230C Variant Is Associated with Decreased Risk of Premature Coronary Artery Disease: The Genetics of Atherosclerotic Disease (GEA) Study
|
|---|---|
| Published in |
PLOS ONE, November 2012
|
| DOI | 10.1371/journal.pone.0049285 |
| Pubmed ID | |
| Authors |
Teresa Villarreal-Molina, Carlos Posadas-Romero, Sandra Romero-Hidalgo, Erika Antúnez-Argüelles, Araceli Bautista-Grande, Gilberto Vargas-Alarcón, Eric Kimura-Hayama, Samuel Canizales-Quinteros, Juan Gabriel Juárez-Rojas, Rosalinda Posadas-Sánchez, Guillermo Cardoso-Saldaña, Aída Medina-Urrutia, María del Carmen González-Salazar, Rocío Martínez-Alvarado, Esteban Jorge-Galarza, Alessandra Carnevale |
| Abstract |
ABCA1 genetic variation is known to play a role in HDL-C levels and various studies have also implicated ABCA1 variation in cardiovascular risk. The functional ABCA1/R230C variant is frequent in the Mexican population and has been consistently associated with low HDL-C concentrations. Although it has been associated with other cardiovascular risk factors such as obesity and type 2 diabetes mellitus, it is not known whether it is associated with coronary artery disease (CAD). |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| Mexico | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 4 | 3% |
| Portugal | 1 | <1% |
| Unknown | 110 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 17% |
| Student > Bachelor | 17 | 15% |
| Researcher | 15 | 13% |
| Student > Ph. D. Student | 13 | 11% |
| Student > Doctoral Student | 7 | 6% |
| Other | 18 | 16% |
| Unknown | 25 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 23% |
| Biochemistry, Genetics and Molecular Biology | 25 | 22% |
| Agricultural and Biological Sciences | 8 | 7% |
| Nursing and Health Professions | 3 | 3% |
| Immunology and Microbiology | 3 | 3% |
| Other | 18 | 16% |
| Unknown | 32 | 28% |