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Metformin Inhibits Glutaminase Activity and Protects against Hepatic Encephalopathy

Overview of attention for article published in PLOS ONE, November 2012
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Title
Metformin Inhibits Glutaminase Activity and Protects against Hepatic Encephalopathy
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0049279
Pubmed ID
Authors

Javier Ampuero, Isidora Ranchal, David Nuñez, María del Mar Díaz-Herrero, Marta Maraver, José Antonio del Campo, Ángela Rojas, Inés Camacho, Blanca Figueruela, Juan D. Bautista, Manuel Romero-Gómez

Abstract

To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ammonia production in vitro.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 4%
Italy 1 2%
Canada 1 2%
Brazil 1 2%
Unknown 51 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 21%
Student > Bachelor 6 11%
Student > Postgraduate 5 9%
Other 4 7%
Student > Ph. D. Student 4 7%
Other 14 25%
Unknown 11 20%
Readers by discipline Count As %
Medicine and Dentistry 17 30%
Agricultural and Biological Sciences 11 20%
Biochemistry, Genetics and Molecular Biology 5 9%
Neuroscience 2 4%
Immunology and Microbiology 2 4%
Other 5 9%
Unknown 14 25%