Title |
Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen
|
---|---|
Published in |
PLOS ONE, November 2012
|
DOI | 10.1371/journal.pone.0049226 |
Pubmed ID | |
Authors |
Yveta Lhotáková, Lukáš Plíštil, Alena Morávková, Pavel Kubát, Kamil Lang, Jitka Forstová, Jiří Mosinger |
Abstract |
Novel biomaterials based on hydrophilic polycaprolactone and polyurethane (Tecophilic®) nanofibers with an encapsulated 5,10,5,20-tetraphenylporphyrin photosensitizer were prepared by electrospinning. The doped nanofiber textiles efficiently photo-generate O(2)((1)Δ(g)), which oxidize external chemical and biological substrates/targets. Strong photo-virucidal effects toward non-enveloped polyomaviruses and enveloped baculoviruses were observed on the surface of these textiles. The photo-virucidal effect was confirmed by a decrease in virus infectivity. In contrast, no virucidal effect was detected in the absence of light and/or the encapsulated photosensitizer. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Philippines | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 60 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 25% |
Student > Ph. D. Student | 13 | 22% |
Student > Bachelor | 8 | 13% |
Student > Master | 8 | 13% |
Other | 3 | 5% |
Other | 7 | 12% |
Unknown | 6 | 10% |
Readers by discipline | Count | As % |
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Chemistry | 27 | 45% |
Engineering | 9 | 15% |
Agricultural and Biological Sciences | 3 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 7 | 12% |
Unknown | 10 | 17% |