Title |
Metabolic Engineering Plant Seeds with Fish Oil-Like Levels of DHA
|
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Published in |
PLOS ONE, November 2012
|
DOI | 10.1371/journal.pone.0049165 |
Pubmed ID | |
Authors |
James R. Petrie, Pushkar Shrestha, Xue-Rong Zhou, Maged P. Mansour, Qing Liu, Srinivas Belide, Peter D. Nichols, Surinder P. Singh |
Abstract |
Omega-3 long-chain (≥C(20)) polyunsaturated fatty acids (ω3 LC-PUFA) have critical roles in human health and development with studies indicating that deficiencies in these fatty acids can increase the risk or severity of cardiovascular and inflammatory diseases in particular. These fatty acids are predominantly sourced from fish and algal oils, but it is widely recognised that there is an urgent need for an alternative and sustainable source of EPA and DHA. Since the earliest demonstrations of ω3 LC-PUFA engineering there has been good progress in engineering the C(20) EPA with seed fatty acid levels similar to that observed in bulk fish oil (∼18%), although undesirable ω6 PUFA levels have also remained high. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 28% |
Canada | 2 | 11% |
Sweden | 2 | 11% |
Chile | 2 | 11% |
Slovakia | 1 | 6% |
Unknown | 6 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 61% |
Scientists | 4 | 22% |
Practitioners (doctors, other healthcare professionals) | 3 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Portugal | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 130 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 16% |
Researcher | 21 | 16% |
Student > Master | 19 | 14% |
Student > Bachelor | 15 | 11% |
Student > Doctoral Student | 5 | 4% |
Other | 16 | 12% |
Unknown | 36 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 56 | 42% |
Biochemistry, Genetics and Molecular Biology | 10 | 7% |
Nursing and Health Professions | 6 | 4% |
Chemistry | 6 | 4% |
Medicine and Dentistry | 3 | 2% |
Other | 12 | 9% |
Unknown | 41 | 31% |