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Inconsistent Definitions for Intention-To-Treat in Relation to Missing Outcome Data: Systematic Review of the Methods Literature

Overview of attention for article published in PLOS ONE, November 2012
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Title
Inconsistent Definitions for Intention-To-Treat in Relation to Missing Outcome Data: Systematic Review of the Methods Literature
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0049163
Pubmed ID
Authors

Mohamad Alshurafa, Matthias Briel, Elie A. Akl, Ted Haines, Paul Moayyedi, Stephen J. Gentles, Lorena Rios, Chau Tran, Neera Bhatnagar, Francois Lamontagne, Stephen D. Walter, Gordon H. Guyatt

Abstract

Authors of randomized trial reports seem to hold a variety of views regarding the relationship between missing outcome data (MOD) and intention to treat (ITT). The objectives of this study were to systematically investigate how authors of methodology articles define ITT in the presence of MOD, how they recommend handling MOD under ITT, and to make a proposal for potential improvement in the definition and use of ITT in relation to MOD.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
United States 2 1%
Canada 2 1%
France 1 <1%
Korea, Republic of 1 <1%
Greece 1 <1%
Peru 1 <1%
Unknown 137 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 20%
Researcher 27 18%
Student > Master 23 16%
Professor 12 8%
Other 9 6%
Other 25 17%
Unknown 21 14%
Readers by discipline Count As %
Medicine and Dentistry 47 32%
Psychology 14 10%
Nursing and Health Professions 14 10%
Social Sciences 10 7%
Agricultural and Biological Sciences 8 5%
Other 23 16%
Unknown 31 21%