| Title |
Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model
|
|---|---|
| Published in |
PLOS ONE, November 2012
|
| DOI | 10.1371/journal.pone.0048468 |
| Pubmed ID | |
| Authors |
Nuria E. Cabrera-Benitez, Eduardo Pérez-Roth, Milena Casula, Ángela Ramos-Nuez, Carla Ríos-Luci, Carlos Rodríguez-Gallego, Ithaisa Sologuren, Virginija Jakubkiene, Arthur S. Slutsky, José M. Padrón, Jesús Villar |
| Abstract |
Despite our increased understanding of the mechanisms involved in acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS), there is no specific pharmacological treatment of proven benefit. We used a novel screening methodology to examine potential anti-inflammatory effects of a small structure-focused library of synthetic carbamate and urea derivatives in a well established cell model of lipopolysaccharide (LPS)-induced ALI/ARDS. |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 3% |
| United States | 1 | 3% |
| France | 1 | 3% |
| Unknown | 34 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 22% |
| Student > Ph. D. Student | 5 | 14% |
| Other | 3 | 8% |
| Student > Master | 3 | 8% |
| Student > Doctoral Student | 2 | 5% |
| Other | 10 | 27% |
| Unknown | 6 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 32% |
| Medicine and Dentistry | 8 | 22% |
| Veterinary Science and Veterinary Medicine | 3 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 8% |
| Chemistry | 2 | 5% |
| Other | 2 | 5% |
| Unknown | 7 | 19% |