| Title |
Ivermectin Inhibits Growth of Chlamydia trachomatis in Epithelial Cells
|
|---|---|
| Published in |
PLOS ONE, October 2012
|
| DOI | 10.1371/journal.pone.0048456 |
| Pubmed ID | |
| Authors |
Matthew A. Pettengill, Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M. Ojcius |
| Abstract |
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans. However, ivermectin has never been shown to be effective against bacterial pathogens. Here we show that ivermectin also inhibits infection of epithelial cells by the bacterial pathogen, Chlamydia trachomatis, at doses that could be envisioned clinically for sexually-transmitted or ocular infections by Chlamydia. |
X Demographics
The data shown below were collected from the profiles of 27 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 22% |
| United Kingdom | 2 | 7% |
| Peru | 1 | 4% |
| Canada | 1 | 4% |
| Australia | 1 | 4% |
| Switzerland | 1 | 4% |
| Japan | 1 | 4% |
| Oman | 1 | 4% |
| France | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 12 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 81% |
| Scientists | 3 | 11% |
| Practitioners (doctors, other healthcare professionals) | 2 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 37 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 22% |
| Student > Bachelor | 5 | 14% |
| Student > Ph. D. Student | 5 | 14% |
| Student > Master | 4 | 11% |
| Other | 3 | 8% |
| Other | 7 | 19% |
| Unknown | 5 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 27% |
| Biochemistry, Genetics and Molecular Biology | 5 | 14% |
| Medicine and Dentistry | 4 | 11% |
| Immunology and Microbiology | 2 | 5% |
| Veterinary Science and Veterinary Medicine | 2 | 5% |
| Other | 7 | 19% |
| Unknown | 7 | 19% |