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NT-ProBNP Levels in Saliva and Its Clinical Relevance to Heart Failure

Overview of attention for article published in PLOS ONE, October 2012
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Title
NT-ProBNP Levels in Saliva and Its Clinical Relevance to Heart Failure
Published in
PLOS ONE, October 2012
DOI 10.1371/journal.pone.0048452
Pubmed ID
Authors

Jared Yong Yang Foo, Yunxia Wan, Karam Kostner, Alicia Arivalagan, John Atherton, Justin Cooper-White, Goce Dimeski, Chamindie Punyadeera

Abstract

Current blood based diagnostic assays to detect heart failure (HF) have large intra-individual and inter-individual variations which have made it difficult to determine whether the changes in the analyte levels reflect an actual change in disease activity. Human saliva mirrors the body's health and well being and ∼20% of proteins that are present in blood are also found in saliva. Saliva has numerous advantages over blood as a diagnostic fluid which allows for a non-invasive, simple, and safe sample collection. The aim of our study was to develop an immunoassay to detect NT-proBNP in saliva and to determine if there is a correlation with blood levels.

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The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 66 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 12%
Researcher 7 11%
Student > Bachelor 7 11%
Student > Master 6 9%
Professor 4 6%
Other 8 12%
Unknown 26 39%
Readers by discipline Count As %
Medicine and Dentistry 14 21%
Engineering 5 8%
Agricultural and Biological Sciences 5 8%
Biochemistry, Genetics and Molecular Biology 3 5%
Nursing and Health Professions 2 3%
Other 6 9%
Unknown 31 47%