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Measurement and Correction of Microscopic Head Motion during Magnetic Resonance Imaging of the Brain

Overview of attention for article published in PLOS ONE, November 2012
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Title
Measurement and Correction of Microscopic Head Motion during Magnetic Resonance Imaging of the Brain
Published in
PLOS ONE, November 2012
DOI 10.1371/journal.pone.0048088
Pubmed ID
Authors

Julian Maclaren, Brian S. R. Armstrong, Robert T. Barrows, K. A. Danishad, Thomas Ernst, Colin L. Foster, Kazim Gumus, Michael Herbst, Ilja Y. Kadashevich, Todd P. Kusik, Qiaotian Li, Cris Lovell-Smith, Thomas Prieto, Peter Schulze, Oliver Speck, Daniel Stucht, Maxim Zaitsev

Abstract

Magnetic resonance imaging (MRI) is a widely used method for non-invasive study of the structure and function of the human brain. Increasing magnetic field strengths enable higher resolution imaging; however, long scan times and high motion sensitivity mean that image quality is often limited by the involuntary motion of the subject. Prospective motion correction is a technique that addresses this problem by tracking head motion and continuously updating the imaging pulse sequence, locking the imaging volume position and orientation relative to the moving brain. The accuracy and precision of current MR-compatible tracking systems and navigator methods allows the quantification and correction of large-scale motion, but not the correction of very small involuntary movements in six degrees of freedom. In this work, we present an MR-compatible tracking system comprising a single camera and a single 15 mm marker that provides tracking precision in the order of 10 m and 0.01 degrees. We show preliminary results, which indicate that when used for prospective motion correction, the system enables improvement in image quality at both 3 T and 7 T, even in experienced and cooperative subjects trained to remain motionless during imaging. We also report direct observation and quantification of the mechanical ballistocardiogram (BCG) during simultaneous MR imaging. This is particularly apparent in the head-feet direction, with a peak-to-peak displacement of 140 m.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 5 3%
United States 2 1%
Netherlands 2 1%
Denmark 2 1%
Switzerland 1 <1%
Canada 1 <1%
Unknown 165 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 48 27%
Researcher 46 26%
Student > Master 18 10%
Professor > Associate Professor 11 6%
Student > Bachelor 6 3%
Other 16 9%
Unknown 33 19%
Readers by discipline Count As %
Engineering 42 24%
Neuroscience 21 12%
Physics and Astronomy 21 12%
Medicine and Dentistry 20 11%
Psychology 8 4%
Other 13 7%
Unknown 53 30%