Title |
Dissociation between Brain Amyloid Deposition and Metabolism in Early Mild Cognitive Impairment
|
---|---|
Published in |
PLOS ONE, October 2012
|
DOI | 10.1371/journal.pone.0047905 |
Pubmed ID | |
Authors |
Liyong Wu, Jared Rowley, Sara Mohades, Antoine Leuzy, Marina Tedeschi Dauar, Monica Shin, Vladimir Fonov, Jianping Jia, Serge Gauthier, Pedro Rosa-Neto, the Alzheimer’s Disease Neuroimaging Initiative |
Abstract |
The hypothetical model of dynamic biomarkers for Alzheimer's disease (AD) describes high amyloid deposition and hypometabolism at the mild cognitive impairment (MCI) stage. However, it remains unknown whether brain amyloidosis and hypometabolism follow the same trajectories in MCI individuals. We used the concept of early MCI (EMCI) and late MCI (LMCI) as defined by the Alzheimer's disease Neuroimaging Initiative (ADNI)-Go in order to compare the biomarker profile between EMCI and LMCI. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Egypt | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
United States | 1 | 1% |
Unknown | 78 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 15% |
Researcher | 10 | 13% |
Student > Ph. D. Student | 9 | 11% |
Professor | 7 | 9% |
Student > Bachelor | 6 | 8% |
Other | 19 | 24% |
Unknown | 17 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 12 | 15% |
Medicine and Dentistry | 11 | 14% |
Psychology | 10 | 13% |
Agricultural and Biological Sciences | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Other | 12 | 15% |
Unknown | 28 | 35% |