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RANTES Gene G-403A Polymorphism and Coronary Artery Disease: A Meta Analysis of Observational Studies

Overview of attention for article published in PLOS ONE, October 2012
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Title
RANTES Gene G-403A Polymorphism and Coronary Artery Disease: A Meta Analysis of Observational Studies
Published in
PLOS ONE, October 2012
DOI 10.1371/journal.pone.0047211
Pubmed ID
Authors

Jun Liu, Yan-Jun Jia, Xiao-Lin Li, Rui-Xa Xu, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Jian-Jun Li

Abstract

The G-403A polymorphism in RANTES gene may be involved in the development of coronary artery disease (CAD) through increasing RANTES-mediated leukocyte trafficking and activation. However, studies investigating the relationship between G-403A polymorphism and CAD yielded contradictory and inconclusive results. In order to shed some light on these inconsistent findings, a meta analysis was performed to clarify the role of G-403A polymorphism of RANTES gene in the susceptibility of CAD.

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Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 40%
Student > Master 2 40%
Student > Doctoral Student 1 20%
Readers by discipline Count As %
Medicine and Dentistry 2 40%
Environmental Science 1 20%
Economics, Econometrics and Finance 1 20%
Biochemistry, Genetics and Molecular Biology 1 20%