Title |
Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes
|
---|---|
Published in |
PLOS ONE, October 2012
|
DOI | 10.1371/journal.pone.0046874 |
Pubmed ID | |
Authors |
Deyi Xiao, Joanna Ohlendorf, Yinlu Chen, Douglas D. Taylor, Shesh N. Rai, Sabine Waigel, Wolfgang Zacharias, Hongying Hao, Kelly M. McMasters |
Abstract |
Exosomes are small membranous vesicles secreted into body fluids by multiple cell types, including tumor cells, and in various disease conditions. Tumor exosomes contain intact and functional mRNAs, small RNAs (including miRNAs), and proteins that can alter the cellular environment to favor tumor growth. Molecular profiling may increase our understanding of the role of exosomes in melanoma progression and may lead to discovery of useful biomarkers. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | 60% |
India | 1 | 10% |
Peru | 1 | 10% |
Unknown | 2 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 90% |
Science communicators (journalists, bloggers, editors) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 338 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | <1% |
Turkey | 2 | <1% |
Chile | 2 | <1% |
Spain | 2 | <1% |
Brazil | 1 | <1% |
South Africa | 1 | <1% |
United Kingdom | 1 | <1% |
Germany | 1 | <1% |
Belgium | 1 | <1% |
Other | 3 | <1% |
Unknown | 321 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 85 | 25% |
Researcher | 74 | 22% |
Student > Master | 38 | 11% |
Student > Bachelor | 22 | 7% |
Student > Postgraduate | 14 | 4% |
Other | 33 | 10% |
Unknown | 72 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 106 | 31% |
Biochemistry, Genetics and Molecular Biology | 69 | 20% |
Medicine and Dentistry | 39 | 12% |
Engineering | 9 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 2% |
Other | 22 | 7% |
Unknown | 85 | 25% |