Title |
Dynamics of Yersinia pestis and Its Antibody Response in Great Gerbils (Rhombomys opimus) by Subcutaneous Infection
|
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Published in |
PLOS ONE, October 2012
|
DOI | 10.1371/journal.pone.0046820 |
Pubmed ID | |
Authors |
Yujiang Zhang, Xiang Dai, Xinhui Wang, Abulimiti Maituohuti, Yujun Cui, Azhati Rehemu, Qiguo Wang, Weiwei Meng, Tao Luo, Rong Guo, Bing Li, Abulikemu Abudurexiti, Yajun Song, Ruifu Yang, Hanli Cao |
Abstract |
Rhombomys opimus (great gerbil) is a reservoir of Yersinia pestis in the natural plague foci of Central Asia. Great gerbils are highly resistant to Y. pestis infection. The coevolution of great gerbils and Y. pestis is believed to play an important role in the plague epidemics in Central Asia plague foci. However, the dynamics of Y. pestis infection and the corresponding antibody response in great gerbils have not been evaluated. In this report, animal experiments were employed to investigate the bacterial load in both the liver and spleen of infected great gerbils. The dynamics of the antibody response to the F1 capsule antigen of Y. pestis was also determined. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 4% |
Norway | 1 | 4% |
Unknown | 26 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 18% |
Researcher | 5 | 18% |
Other | 4 | 14% |
Student > Ph. D. Student | 4 | 14% |
Student > Master | 3 | 11% |
Other | 2 | 7% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 29% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Veterinary Science and Veterinary Medicine | 2 | 7% |
Social Sciences | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Other | 6 | 21% |
Unknown | 5 | 18% |