Title |
Comparative Analysis of the Shadoo Gene between Cattle and Buffalo Reveals Significant Differences
|
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Published in |
PLOS ONE, October 2012
|
DOI | 10.1371/journal.pone.0046601 |
Pubmed ID | |
Authors |
Hui Zhao, Lin-Lin Liu, Shou-Hui Du, Si-Qi Wang, Ya-Ping Zhang |
Abstract |
While prions play a central role in the pathogenesis of transmissible spongiform encephalopathies, the biology of these proteins and the pathophysiology of these diseases remain largely unknown. Since no case of bovine spongiform encephalopathy (BSE) has ever been reported in buffalo despite their phylogenetic proximity to cattle, genetic differences may be driving the different susceptibilities of these two species to BSE. We thus hypothesized that differences in expression of the most recently identified member of the prion family or Shadoo (SPRN) gene may relate to these species-specific differences. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 28% |
Researcher | 6 | 21% |
Professor > Associate Professor | 4 | 14% |
Student > Doctoral Student | 3 | 10% |
Student > Master | 3 | 10% |
Other | 3 | 10% |
Unknown | 2 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 45% |
Biochemistry, Genetics and Molecular Biology | 8 | 28% |
Arts and Humanities | 1 | 3% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Computer Science | 1 | 3% |
Other | 0 | 0% |
Unknown | 5 | 17% |