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Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes to Ischemic Stroke Risk: A Meta-Analysis of 50 Case-Control Studies

Overview of attention for article published in PLOS ONE, October 2012
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Title
Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes to Ischemic Stroke Risk: A Meta-Analysis of 50 Case-Control Studies
Published in
PLOS ONE, October 2012
DOI 10.1371/journal.pone.0046495
Pubmed ID
Authors

Zhizhong Zhang, Gelin Xu, Dezhi Liu, Xinying Fan, Wusheng Zhu, Xinfeng Liu

Abstract

Many studies have investigated the association between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and risk of ischemic stroke. However, the evidence is inadequate to draw robust conclusions because most studies were generally small and conducted in heterogeneous populations. To shed light on these inconclusive findings, we conducted a large meta-analysis of studies relating the ACE I/D polymorphism to the risk of ischemic stroke.

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Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
United States 1 2%
Denmark 1 2%
Unknown 48 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 18%
Student > Bachelor 8 16%
Researcher 5 10%
Student > Master 5 10%
Student > Doctoral Student 4 8%
Other 9 18%
Unknown 11 22%
Readers by discipline Count As %
Medicine and Dentistry 13 25%
Biochemistry, Genetics and Molecular Biology 10 20%
Agricultural and Biological Sciences 8 16%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Environmental Science 1 2%
Other 4 8%
Unknown 13 25%