Title |
The Geographical Distribution of Leadership in Globalized Clinical Trials
|
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Published in |
PLOS ONE, October 2012
|
DOI | 10.1371/journal.pone.0045984 |
Pubmed ID | |
Authors |
Jarno Hoekman, Koen Frenken, Dick de Zeeuw, Hiddo Lambers Heerspink |
Abstract |
Pharmaceutical trials are mainly initiated by sponsors and investigators in the United States, Western Europe and Japan. However, more and more patients are enrolled in Central and Eastern Europe, Latin America and Asia. The involvement of patients in new geographical settings raises questions about scientific and ethical integrity, especially when experience with those settings is lacking at the level of trial management. We therefore studied to what extent the geographical shift in patient enrolment is anticipated in the composition of trial management teams using the author nationalities on the primary outcome publication as an indicator of leadership. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 25% |
Ireland | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 2% |
Canada | 1 | 2% |
Unknown | 49 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 20% |
Researcher | 7 | 14% |
Student > Ph. D. Student | 7 | 14% |
Student > Doctoral Student | 4 | 8% |
Student > Bachelor | 4 | 8% |
Other | 6 | 12% |
Unknown | 13 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 16% |
Agricultural and Biological Sciences | 6 | 12% |
Social Sciences | 5 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
Other | 13 | 25% |
Unknown | 13 | 25% |