Title |
A Randomized Trial of Selenium Supplementation and Risk of Type-2 Diabetes, as Assessed by Plasma Adiponectin
|
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Published in |
PLOS ONE, September 2012
|
DOI | 10.1371/journal.pone.0045269 |
Pubmed ID | |
Authors |
Margaret P. Rayman, Gabrielle Blundell-Pound, Roberto Pastor-Barriuso, Eliseo Guallar, Holger Steinbrenner, Saverio Stranges |
Abstract |
Evidence that selenium affects the risk of type-2 diabetes is conflicting, with observational studies and a few randomized trials showing both lower and higher risk linked to the level of selenium intake and status. We investigated the effect of selenium supplementation on the risk of type-2 diabetes in a population of relatively low selenium status as part of the UK PRECISE (PREvention of Cancer by Intervention with SElenium) pilot study. Plasma adiponectin concentration, a recognised independent predictor of type-2 diabetes risk and known to be correlated with circulating selenoprotein P, was the biomarker chosen. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 1 | <1% |
Australia | 1 | <1% |
Denmark | 1 | <1% |
Spain | 1 | <1% |
Poland | 1 | <1% |
Unknown | 128 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 26 | 20% |
Student > Ph. D. Student | 20 | 15% |
Student > Bachelor | 19 | 14% |
Student > Master | 16 | 12% |
Student > Postgraduate | 7 | 5% |
Other | 26 | 20% |
Unknown | 19 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 44 | 33% |
Agricultural and Biological Sciences | 17 | 13% |
Nursing and Health Professions | 17 | 13% |
Biochemistry, Genetics and Molecular Biology | 9 | 7% |
Sports and Recreations | 3 | 2% |
Other | 14 | 11% |
Unknown | 29 | 22% |