| Title |
Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck Cancer
|
|---|---|
| Published in |
PLOS ONE, August 2012
|
| DOI | 10.1371/journal.pone.0044488 |
| Pubmed ID | |
| Authors |
Yasusei Kudo, Shinji Iizuka, Maki Yoshida, Phuong Thao Nguyen, Samadarani B. S. M. Siriwardena, Takaaki Tsunematsu, Mariko Ohbayashi, Toshinori Ando, Daijiro Hatakeyama, Toshiyuki Shibata, Keiichi Koizumi, Masahiro Maeda, Naozumi Ishimaru, Ikuko Ogawa, Takashi Takata |
| Abstract |
Metastasis to regional lymph nodes via lymphatic vessels plays a key role in cancer progression. Tumor lymphangiogenesis is known to promote lymphatic metastasis, and vascular endothelial growth factor C (VEGF-C) is a critical activator of tumor lymphangiogenesis during the process of metastasis. We previously identified periostin as an invasion- and angiogenesis-promoting factor in head and neck squamous cell carcinoma (HNSCC). In this study, we discovered a novel role for periostin in tumor lymphangiogenesis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 21% |
| Student > Ph. D. Student | 10 | 19% |
| Other | 5 | 10% |
| Student > Bachelor | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 13 | 25% |
| Unknown | 5 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 33% |
| Agricultural and Biological Sciences | 11 | 21% |
| Biochemistry, Genetics and Molecular Biology | 8 | 15% |
| Engineering | 3 | 6% |
| Chemical Engineering | 1 | 2% |
| Other | 3 | 6% |
| Unknown | 9 | 17% |