| Title |
Telomere Dynamics and Homeostasis in a Transmissible Cancer
|
|---|---|
| Published in |
PLOS ONE, August 2012
|
| DOI | 10.1371/journal.pone.0044085 |
| Pubmed ID | |
| Authors |
Beata Ujvari, Anne-Maree Pearse, Robyn Taylor, Stephen Pyecroft, Cassandra Flanagan, Sara Gombert, Anthony T. Papenfuss, Thomas Madsen, Katherine Belov |
| Abstract |
Devil Facial Tumour Disease (DFTD) is a unique clonal cancer that threatens the world's largest carnivorous marsupial, the Tasmanian devil (Sarcophilus harrisii) with extinction. This transmissible cancer is passed between individual devils by cell implantation during social interactions. The tumour arose in a Schwann cell of a single devil over 15 years ago and since then has expanded clonally, without showing signs of replicative senescence; in stark contrast to a somatic cell that displays a finite capacity for replication, known as the "Hayflick limit". |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 83% |
| Members of the public | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Romania | 1 | 2% |
| Unknown | 53 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 27% |
| Student > Master | 12 | 21% |
| Student > Ph. D. Student | 6 | 11% |
| Student > Postgraduate | 6 | 11% |
| Student > Bachelor | 5 | 9% |
| Other | 7 | 13% |
| Unknown | 5 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 50% |
| Immunology and Microbiology | 7 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Veterinary Science and Veterinary Medicine | 3 | 5% |
| Environmental Science | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 6 | 11% |