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Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren's Disease

Overview of attention for article published in PLOS ONE, August 2012
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Title
Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren's Disease
Published in
PLOS ONE, August 2012
DOI 10.1371/journal.pone.0043406
Pubmed ID
Authors

Warren M. Rozen, Yasith Edirisinghe, John Crock

Abstract

While Dupuytren's disease can cause disabling contractures requiring open surgery, a less-invasive option using Clostridium Histolyticum collagenase (CHC) via percutaneous injection was recently reported. A recent prospective, randomized trial demonstrated few complications during 90 days follow-up, however did not assess any longer term follow-up for these patients. Long-term outcomes in this setting have not been adequately reported, and the current manuscript aims to identify late complications from the clinical use of percutaneous CHC.

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Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Italy 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 20%
Other 7 16%
Student > Bachelor 7 16%
Professor 5 11%
Student > Ph. D. Student 4 9%
Other 5 11%
Unknown 7 16%
Readers by discipline Count As %
Medicine and Dentistry 22 50%
Nursing and Health Professions 3 7%
Engineering 3 7%
Agricultural and Biological Sciences 3 7%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 4 9%
Unknown 8 18%