Title |
Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren's Disease
|
---|---|
Published in |
PLOS ONE, August 2012
|
DOI | 10.1371/journal.pone.0043406 |
Pubmed ID | |
Authors |
Warren M. Rozen, Yasith Edirisinghe, John Crock |
Abstract |
While Dupuytren's disease can cause disabling contractures requiring open surgery, a less-invasive option using Clostridium Histolyticum collagenase (CHC) via percutaneous injection was recently reported. A recent prospective, randomized trial demonstrated few complications during 90 days follow-up, however did not assess any longer term follow-up for these patients. Long-term outcomes in this setting have not been adequately reported, and the current manuscript aims to identify late complications from the clinical use of percutaneous CHC. |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Italy | 1 | 2% |
Unknown | 42 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 20% |
Other | 7 | 16% |
Student > Bachelor | 7 | 16% |
Professor | 5 | 11% |
Student > Ph. D. Student | 4 | 9% |
Other | 5 | 11% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 50% |
Nursing and Health Professions | 3 | 7% |
Engineering | 3 | 7% |
Agricultural and Biological Sciences | 3 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 4 | 9% |
Unknown | 8 | 18% |