| Title |
Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice
|
|---|---|
| Published in |
PLOS ONE, August 2012
|
| DOI | 10.1371/journal.pone.0042422 |
| Pubmed ID | |
| Authors |
Ozlem Bozdagi, Takeshi Sakurai, Nathan Dorr, Marion Pilorge, Nagahide Takahashi, Joseph D. Buxbaum |
| Abstract |
Copy number variation (CNV) at the 15q11.2 region, which includes a gene that codes for CYFIP1 (cytoplasmic FMR1 interacting protein 1), has been implicated in autism, intellectual disability and additional neuropsychiatric phenotypes. In the current study we studied the function of Cyfip1 in synaptic physiology and behavior, using mice with a disruption of the Cyfip1 gene. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 122 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 22% |
| Researcher | 24 | 18% |
| Student > Bachelor | 15 | 12% |
| Student > Master | 10 | 8% |
| Professor | 7 | 5% |
| Other | 23 | 18% |
| Unknown | 23 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 33% |
| Neuroscience | 20 | 15% |
| Medicine and Dentistry | 15 | 12% |
| Biochemistry, Genetics and Molecular Biology | 12 | 9% |
| Psychology | 8 | 6% |
| Other | 10 | 8% |
| Unknown | 22 | 17% |