Title |
β-D-glucan Surveillance with Preemptive Anidulafungin for Invasive Candidiasis in Intensive Care Unit Patients: A Randomized Pilot Study
|
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Published in |
PLOS ONE, August 2012
|
DOI | 10.1371/journal.pone.0042282 |
Pubmed ID | |
Authors |
Kimberly E. Hanson, Christopher D. Pfeiffer, Erika D. Lease, Alfred H. Balch, Aimee K. Zaas, John R. Perfect, Barbara D. Alexander |
Abstract |
Invasive candidiasis (IC) is a devastating disease. While prompt antifungal therapy improves outcomes, empiric treatment based on the presence of fever has little clinical impact. Β-D-Glucan (BDG) is a fungal cell wall component detectable in the serum of patients with early invasive fungal infection (IFI). We evaluated the utility of BDG surveillance as a guide for preemptive antifungal therapy in at-risk intensive care unit (ICU) patients. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Denmark | 1 | <1% |
Germany | 1 | <1% |
Australia | 1 | <1% |
Unknown | 100 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 14% |
Other | 12 | 12% |
Student > Ph. D. Student | 9 | 9% |
Student > Master | 8 | 8% |
Student > Doctoral Student | 8 | 8% |
Other | 27 | 26% |
Unknown | 25 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 51 | 49% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
Agricultural and Biological Sciences | 5 | 5% |
Immunology and Microbiology | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Other | 7 | 7% |
Unknown | 28 | 27% |