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β-D-glucan Surveillance with Preemptive Anidulafungin for Invasive Candidiasis in Intensive Care Unit Patients: A Randomized Pilot Study

Overview of attention for article published in PLOS ONE, August 2012
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Title
β-D-glucan Surveillance with Preemptive Anidulafungin for Invasive Candidiasis in Intensive Care Unit Patients: A Randomized Pilot Study
Published in
PLOS ONE, August 2012
DOI 10.1371/journal.pone.0042282
Pubmed ID
Authors

Kimberly E. Hanson, Christopher D. Pfeiffer, Erika D. Lease, Alfred H. Balch, Aimee K. Zaas, John R. Perfect, Barbara D. Alexander

Abstract

Invasive candidiasis (IC) is a devastating disease. While prompt antifungal therapy improves outcomes, empiric treatment based on the presence of fever has little clinical impact. Β-D-Glucan (BDG) is a fungal cell wall component detectable in the serum of patients with early invasive fungal infection (IFI). We evaluated the utility of BDG surveillance as a guide for preemptive antifungal therapy in at-risk intensive care unit (ICU) patients.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Denmark 1 <1%
Germany 1 <1%
Australia 1 <1%
Unknown 100 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 14%
Other 12 12%
Student > Ph. D. Student 9 9%
Student > Master 8 8%
Student > Doctoral Student 8 8%
Other 27 26%
Unknown 25 24%
Readers by discipline Count As %
Medicine and Dentistry 51 49%
Pharmacology, Toxicology and Pharmaceutical Science 6 6%
Agricultural and Biological Sciences 5 5%
Immunology and Microbiology 4 4%
Nursing and Health Professions 3 3%
Other 7 7%
Unknown 28 27%