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Stavudine Toxicity in Adult Longer-Term ART Patients in Blantyre, Malawi

Overview of attention for article published in PLOS ONE, July 2012
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Title
Stavudine Toxicity in Adult Longer-Term ART Patients in Blantyre, Malawi
Published in
PLOS ONE, July 2012
DOI 10.1371/journal.pone.0042029
Pubmed ID
Authors

Joep J. van Oosterhout, Jane Mallewa, Symon Kaunda, Newton Chagoma, Yassin Njalale, Elizabeth Kampira, Mavuto Mukaka, Robert S. Heyderman

Abstract

Stavudine is an effective and inexpensive antiretroviral drug, but no longer recommended by WHO for first-line antiretroviral regimens in resource-limited settings due to toxicity concerns. Because of the high cost of alternative drugs, it has not been feasible to replace stavudine in most adults in the Malawi ART programme. We aimed to provide policy makers with a detailed picture of stavudine toxicities in Malawians on longer-term ART, in order to facilitate prioritization of stavudine replacement among other measures to improve the quality of ART programmes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 2%
Denmark 1 1%
United Kingdom 1 1%
Unknown 87 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 18%
Student > Master 13 14%
Student > Ph. D. Student 7 8%
Student > Bachelor 5 5%
Student > Doctoral Student 5 5%
Other 23 25%
Unknown 22 24%
Readers by discipline Count As %
Medicine and Dentistry 24 26%
Social Sciences 12 13%
Nursing and Health Professions 7 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Agricultural and Biological Sciences 4 4%
Other 13 14%
Unknown 26 29%