Title |
Stavudine Toxicity in Adult Longer-Term ART Patients in Blantyre, Malawi
|
---|---|
Published in |
PLOS ONE, July 2012
|
DOI | 10.1371/journal.pone.0042029 |
Pubmed ID | |
Authors |
Joep J. van Oosterhout, Jane Mallewa, Symon Kaunda, Newton Chagoma, Yassin Njalale, Elizabeth Kampira, Mavuto Mukaka, Robert S. Heyderman |
Abstract |
Stavudine is an effective and inexpensive antiretroviral drug, but no longer recommended by WHO for first-line antiretroviral regimens in resource-limited settings due to toxicity concerns. Because of the high cost of alternative drugs, it has not been feasible to replace stavudine in most adults in the Malawi ART programme. We aimed to provide policy makers with a detailed picture of stavudine toxicities in Malawians on longer-term ART, in order to facilitate prioritization of stavudine replacement among other measures to improve the quality of ART programmes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 2 | 2% |
Denmark | 1 | 1% |
United Kingdom | 1 | 1% |
Unknown | 87 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 18% |
Student > Master | 13 | 14% |
Student > Ph. D. Student | 7 | 8% |
Student > Bachelor | 5 | 5% |
Student > Doctoral Student | 5 | 5% |
Other | 23 | 25% |
Unknown | 22 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 26% |
Social Sciences | 12 | 13% |
Nursing and Health Professions | 7 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
Agricultural and Biological Sciences | 4 | 4% |
Other | 13 | 14% |
Unknown | 26 | 29% |