Title |
Molecular Evolution of GII-4 Norovirus Strains
|
---|---|
Published in |
PLOS ONE, July 2012
|
DOI | 10.1371/journal.pone.0041625 |
Pubmed ID | |
Authors |
Katherina Zakikhany, David J. Allen, David Brown, Miren Iturriza-Gómara |
Abstract |
Human Noroviruses (NoV) are the major cause of acute nonbacterial gastroenteritis and the leading cause of outbreaks of gastroenteritis worldwide. Genotype II-4 (GII-4) NoV has been shown to spread rapidly and is the most commonly detected strain worldwide, particularly in association with outbreaks. Previously, we have shown that circulating GII-4 NoV strains exist as populations of selectively neutral variants, and that the emergence of epidemic GII-4 NoV strains correlated with mutations in at least two key sites (Sites A and B) within the P2 domain of the surface exposed major capsid protein (VP1). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
United States | 1 | 2% |
Unknown | 49 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 31% |
Student > Ph. D. Student | 8 | 16% |
Student > Master | 7 | 14% |
Student > Doctoral Student | 5 | 10% |
Student > Bachelor | 5 | 10% |
Other | 7 | 14% |
Unknown | 3 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 45% |
Immunology and Microbiology | 6 | 12% |
Medicine and Dentistry | 5 | 10% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Environmental Science | 2 | 4% |
Other | 2 | 4% |
Unknown | 8 | 16% |