| Title |
Deep Panning: Steps towards Probing the IgOme
|
|---|---|
| Published in |
PLOS ONE, August 2012
|
| DOI | 10.1371/journal.pone.0041469 |
| Pubmed ID | |
| Authors |
Arie Ryvkin, Haim Ashkenazy, Larisa Smelyanski, Gilad Kaplan, Osnat Penn, Yael Weiss-Ottolenghi, Eyal Privman, Peter B. Ngam, James E. Woodward, Gregory D. May, Callum Bell, Tal Pupko, Jonathan M. Gershoni |
| Abstract |
Polyclonal serum consists of vast collections of antibodies, products of differentiated B-cells. The spectrum of antibody specificities is dynamic and varies with age, physiology, and exposure to pathological insults. The complete repertoire of antibody specificities in blood, the IgOme, is therefore an extraordinarily rich source of information-a molecular record of previous encounters as well as a status report of current immune activity. The ability to profile antibody specificities of polyclonal serum at exceptionally high resolution has been an important and serious challenge which can now be overcome. |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 3% |
| Japan | 2 | 2% |
| Germany | 1 | <1% |
| France | 1 | <1% |
| Unknown | 108 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 28% |
| Student > Ph. D. Student | 22 | 19% |
| Student > Master | 14 | 12% |
| Student > Doctoral Student | 7 | 6% |
| Other | 7 | 6% |
| Other | 20 | 17% |
| Unknown | 13 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 37% |
| Biochemistry, Genetics and Molecular Biology | 21 | 18% |
| Chemistry | 8 | 7% |
| Medicine and Dentistry | 7 | 6% |
| Immunology and Microbiology | 6 | 5% |
| Other | 18 | 16% |
| Unknown | 13 | 11% |