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The Dynamics, Causes and Possible Prevention of Hepatitis E Outbreaks

Overview of attention for article published in PLOS ONE, July 2012
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Title
The Dynamics, Causes and Possible Prevention of Hepatitis E Outbreaks
Published in
PLOS ONE, July 2012
DOI 10.1371/journal.pone.0041135
Pubmed ID
Authors

Betty Nannyonga, David J. T. Sumpter, Joseph Y. T. Mugisha, Livingstone S. Luboobi

Abstract

Rapidly spreading infectious diseases are a serious risk to public health. The dynamics and the factors causing outbreaks of these diseases can be better understood using mathematical models, which are fit to data. Here we investigate the dynamics of a Hepatitis E outbreak in the Kitgum region of northern Uganda during 2007 to 2009. First, we use the data to determine that R0 is approximately 2.25 for the outbreak. Secondly, we use a model to estimate that the critical level of latrine and bore hole coverages needed to eradicate the epidemic is at least 16% and 17% respectively. Lastly, we further investigate the relationship between the co-infection factor for malaria and Hepatitis E on the value of R0 for Hepatitis E. Taken together, these results provide us with a better understanding of the dynamics and possible causes of Hepatitis E outbreaks.

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Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Denmark 1 2%
Unknown 49 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 20%
Student > Master 8 16%
Researcher 8 16%
Student > Doctoral Student 4 8%
Other 4 8%
Other 8 16%
Unknown 9 18%
Readers by discipline Count As %
Medicine and Dentistry 15 29%
Agricultural and Biological Sciences 9 18%
Environmental Science 3 6%
Immunology and Microbiology 3 6%
Nursing and Health Professions 3 6%
Other 7 14%
Unknown 11 22%