Title |
The Dynamics, Causes and Possible Prevention of Hepatitis E Outbreaks
|
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Published in |
PLOS ONE, July 2012
|
DOI | 10.1371/journal.pone.0041135 |
Pubmed ID | |
Authors |
Betty Nannyonga, David J. T. Sumpter, Joseph Y. T. Mugisha, Livingstone S. Luboobi |
Abstract |
Rapidly spreading infectious diseases are a serious risk to public health. The dynamics and the factors causing outbreaks of these diseases can be better understood using mathematical models, which are fit to data. Here we investigate the dynamics of a Hepatitis E outbreak in the Kitgum region of northern Uganda during 2007 to 2009. First, we use the data to determine that R0 is approximately 2.25 for the outbreak. Secondly, we use a model to estimate that the critical level of latrine and bore hole coverages needed to eradicate the epidemic is at least 16% and 17% respectively. Lastly, we further investigate the relationship between the co-infection factor for malaria and Hepatitis E on the value of R0 for Hepatitis E. Taken together, these results provide us with a better understanding of the dynamics and possible causes of Hepatitis E outbreaks. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Denmark | 1 | 2% |
Unknown | 49 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 10 | 20% |
Student > Master | 8 | 16% |
Researcher | 8 | 16% |
Student > Doctoral Student | 4 | 8% |
Other | 4 | 8% |
Other | 8 | 16% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 29% |
Agricultural and Biological Sciences | 9 | 18% |
Environmental Science | 3 | 6% |
Immunology and Microbiology | 3 | 6% |
Nursing and Health Professions | 3 | 6% |
Other | 7 | 14% |
Unknown | 11 | 22% |