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Are There Neurophenotypes for Asthma? Functional Brain Imaging of the Interaction between Emotion and Inflammation in Asthma

Overview of attention for article published in PLOS ONE, August 2012
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Title
Are There Neurophenotypes for Asthma? Functional Brain Imaging of the Interaction between Emotion and Inflammation in Asthma
Published in
PLOS ONE, August 2012
DOI 10.1371/journal.pone.0040921
Pubmed ID
Authors

Melissa A. Rosenkranz, William W. Busse, John F. Sheridan, Gina M. Crisafi, Richard J. Davidson

Abstract

Asthma is a chronic inflammatory disease noteworthy for its vulnerability to stress and emotion-induced symptom intensification. The fact that psychological stress and mood and anxiety disorders appear to increase expression of asthma symptoms suggests that neural signaling between the brain and lung at least partially modulates the inflammatory response and lung function. However, the precise nature of the neural pathways implicated in modulating asthma symptoms is unknown. Moreover, the extent to which variations in neural signaling predict different phenotypes of disease expression has not been studied.

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Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Denmark 1 <1%
Germany 1 <1%
France 1 <1%
Unknown 105 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 28 25%
Student > Ph. D. Student 17 15%
Student > Master 12 11%
Student > Bachelor 8 7%
Professor 6 5%
Other 20 18%
Unknown 19 17%
Readers by discipline Count As %
Psychology 24 22%
Medicine and Dentistry 20 18%
Neuroscience 16 15%
Agricultural and Biological Sciences 8 7%
Unspecified 4 4%
Other 13 12%
Unknown 25 23%