| Title |
Perinatal Maternal Administration of Lactobacillus paracasei NCC 2461 Prevents Allergic Inflammation in a Mouse Model of Birch Pollen Allergy
|
|---|---|
| Published in |
PLOS ONE, July 2012
|
| DOI | 10.1371/journal.pone.0040271 |
| Pubmed ID | |
| Authors |
Irma Schabussova, Karin Hufnagl, Mimi L. K. Tang, Elisabeth Hoflehner, Angelika Wagner, Gerhard Loupal, Sophie Nutten, Adrian Zuercher, Annick Mercenier, Ursula Wiedermann |
| Abstract |
The hygiene hypothesis implies that microbial agents including probiotic bacteria may modulate foetal/neonatal immune programming and hence offer effective strategies for primary allergy prevention; however their mechanisms of action are poorly understood. We investigated whether oral administration of Lactobacillus paracasei NCC 2461 to mothers during gestation/lactation can protect against airway inflammation in offspring in a mouse model of birch pollen allergy, and examined the immune mechanisms involved. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 1% |
| Unknown | 73 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 18% |
| Student > Ph. D. Student | 10 | 14% |
| Student > Bachelor | 10 | 14% |
| Student > Master | 9 | 12% |
| Student > Doctoral Student | 4 | 5% |
| Other | 8 | 11% |
| Unknown | 20 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 19% |
| Medicine and Dentistry | 10 | 14% |
| Immunology and Microbiology | 9 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 8% |
| Nursing and Health Professions | 6 | 8% |
| Other | 7 | 9% |
| Unknown | 22 | 30% |