| Title |
Multi-Target Drugs: The Trend of Drug Research and Development
|
|---|---|
| Published in |
PLOS ONE, June 2012
|
| DOI | 10.1371/journal.pone.0040262 |
| Pubmed ID | |
| Authors |
Jin-Jian Lu, Wei Pan, Yuan-Jia Hu, Yi-Tao Wang |
| Abstract |
Summarizing the status of drugs in the market and examining the trend of drug research and development is important in drug discovery. In this study, we compared the drug targets and the market sales of the new molecular entities approved by the U.S. Food and Drug Administration from January 2000 to December 2009. Two networks, namely, the target-target and drug-drug networks, have been set up using the network analysis tools. The multi-target drugs have much more potential, as shown by the network visualization and the market trends. We discussed the possible reasons and proposed the rational strategies for drug research and development in the future. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 288 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 1% |
| United States | 3 | 1% |
| Spain | 3 | 1% |
| Indonesia | 1 | <1% |
| Pakistan | 1 | <1% |
| Hungary | 1 | <1% |
| Italy | 1 | <1% |
| Austria | 1 | <1% |
| Brazil | 1 | <1% |
| Other | 5 | 2% |
| Unknown | 268 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 74 | 26% |
| Student > Master | 39 | 14% |
| Student > Bachelor | 38 | 13% |
| Researcher | 31 | 11% |
| Student > Postgraduate | 18 | 6% |
| Other | 49 | 17% |
| Unknown | 39 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 66 | 23% |
| Chemistry | 57 | 20% |
| Biochemistry, Genetics and Molecular Biology | 30 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 28 | 10% |
| Medicine and Dentistry | 23 | 8% |
| Other | 28 | 10% |
| Unknown | 56 | 19% |