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Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

Overview of attention for article published in PLOS ONE, July 2012
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Title
Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds
Published in
PLOS ONE, July 2012
DOI 10.1371/journal.pone.0040098
Pubmed ID
Authors

Dipen Rajgor, Jason A. Mellad, Flavia Autore, Qiuping Zhang, Catherine M. Shanahan

Abstract

Nesprins (Nuclear envelope spectrin-repeat proteins) are a novel family of giant spectrin-repeat containing proteins. The nesprin-1 and nesprin-2 genes consist of 146 and 116 exons which encode proteins of ∼1mDa and ∼800 kDa is size respectively when all the exons are utilised in translation. However emerging data suggests that the nesprins have multiple alternative start and termination sites throughout their genes allowing the generation of smaller isoforms.

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Mendeley readers

The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Canada 1 <1%
Argentina 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 95 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 27%
Researcher 20 20%
Student > Bachelor 17 17%
Student > Master 7 7%
Student > Doctoral Student 5 5%
Other 8 8%
Unknown 17 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 35%
Biochemistry, Genetics and Molecular Biology 25 25%
Medicine and Dentistry 7 7%
Engineering 5 5%
Neuroscience 3 3%
Other 6 6%
Unknown 20 20%