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Lack of Association of Two Common Polymorphisms rs2910164 and rs11614913 with Susceptibility to Hepatocellular Carcinoma: A Meta-Analysis

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Title
Lack of Association of Two Common Polymorphisms rs2910164 and rs11614913 with Susceptibility to Hepatocellular Carcinoma: A Meta-Analysis
Published in
PLOS ONE, June 2012
DOI 10.1371/journal.pone.0040039
Pubmed ID
Authors

Zhongxia Wang, Yin Cao, Chunping Jiang, Guang Yang, Junhua Wu, Yitao Ding

Abstract

Single nucleotide polymorphisms (SNPs) in microRNA-coding genes may participate in the process of carcinogenesis by altering the expression of tumor-related microRNAs. It has been suggested that two common SNPs rs2910164 in miR-146a and rs11614913 in miR-196a2 are associated with susceptibility to hepatocellular carcinoma (HCC). However, published results are inconsistent and inconclusive. In the present study, we performed a meta-analysis to systematically summarize the possible association between the two SNPs and the risk for HCC.

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The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 31%
Researcher 2 15%
Other 1 8%
Student > Bachelor 1 8%
Professor 1 8%
Other 3 23%
Unknown 1 8%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 31%
Agricultural and Biological Sciences 3 23%
Medicine and Dentistry 2 15%
Immunology and Microbiology 1 8%
Environmental Science 1 8%
Other 2 15%