Title |
Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study
|
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Published in |
PLOS ONE, June 2012
|
DOI | 10.1371/journal.pone.0039541 |
Pubmed ID | |
Authors |
Melinda C. Aldrich, Rajesh Kumar, Laura A. Colangelo, L. Keoki Williams, Saunak Sen, Stephen B. Kritchevsky, Bernd Meibohm, Joshua Galanter, Donglei Hu, Christopher R. Gignoux, Yongmei Liu, Tamara B. Harris, Elad Ziv, Joseph Zmuda, Melissa Garcia, Tennille S. Leak, Marilyn G. Foreman, Lewis J. Smith, Myriam Fornage, Kiang Liu, Esteban G. Burchard |
Abstract |
Smoking tobacco reduces lung function. African Americans have both lower lung function and decreased metabolism of tobacco smoke compared to European Americans. African ancestry is also associated with lower pulmonary function in African Americans. We aimed to determine whether African ancestry modifies the association between smoking and lung function and its rate of decline in African Americans. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 2% |
Unknown | 51 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 21% |
Researcher | 10 | 19% |
Student > Master | 5 | 10% |
Student > Bachelor | 4 | 8% |
Professor | 4 | 8% |
Other | 8 | 15% |
Unknown | 10 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 29% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Agricultural and Biological Sciences | 5 | 10% |
Nursing and Health Professions | 4 | 8% |
Mathematics | 2 | 4% |
Other | 7 | 13% |
Unknown | 14 | 27% |