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Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study

Overview of attention for article published in PLOS ONE, June 2012
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Title
Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study
Published in
PLOS ONE, June 2012
DOI 10.1371/journal.pone.0039243
Pubmed ID
Authors

Didier Jutras-Aswad, Michelle M. Jacobs, Georgia Yiannoulos, Panos Roussos, Panos Bitsios, Yoko Nomura, Xun Liu, Yasmin L. Hurd

Abstract

Many young people experiment with cannabis, yet only a subgroup progress to dependence suggesting individual differences that could relate to factors such as genetics and behavioral traits. Dopamine receptor D2 (DRD2) and proenkephalin (PENK) genes have been implicated in animal studies with cannabis exposure. Whether polymorphisms of these genes are associated with cannabis dependence and related behavioral traits is unknown.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Unknown 80 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 18%
Researcher 10 12%
Student > Bachelor 10 12%
Student > Ph. D. Student 8 10%
Student > Postgraduate 6 7%
Other 18 22%
Unknown 15 18%
Readers by discipline Count As %
Psychology 18 22%
Medicine and Dentistry 12 15%
Agricultural and Biological Sciences 10 12%
Biochemistry, Genetics and Molecular Biology 7 9%
Neuroscience 6 7%
Other 10 12%
Unknown 19 23%