| Title |
The Safe Use of a PTEN Inhibitor for the Activation of Dormant Mouse Primordial Follicles and Generation of Fertilizable Eggs
|
|---|---|
| Published in |
PLOS ONE, June 2012
|
| DOI | 10.1371/journal.pone.0039034 |
| Pubmed ID | |
| Authors |
Deepak Adhikari, Nagaraju Gorre, Sanjiv Risal, Zhiyi Zhao, Hua Zhang, Yan Shen, Kui Liu |
| Abstract |
Primordial ovarian follicles, which are often present in the ovaries of premature ovarian failure (POF) patients or are cryopreserved from the ovaries of young cancer patients who are undergoing gonadotoxic anticancer therapies, cannot be used to generate mature oocytes for in vitro fertilization (IVF). There has been very little success in triggering growth of primordial follicles to obtain fertilizable oocytes due to the poor understanding of the biology of primordial follicle activation. |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| United Kingdom | 1 | 1% |
| Unknown | 68 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 21% |
| Student > Bachelor | 7 | 10% |
| Researcher | 7 | 10% |
| Student > Master | 6 | 8% |
| Professor > Associate Professor | 5 | 7% |
| Other | 11 | 15% |
| Unknown | 20 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 27% |
| Medicine and Dentistry | 17 | 24% |
| Biochemistry, Genetics and Molecular Biology | 8 | 11% |
| Immunology and Microbiology | 2 | 3% |
| Unspecified | 1 | 1% |
| Other | 2 | 3% |
| Unknown | 22 | 31% |