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Line-Scanning Particle Image Velocimetry: An Optical Approach for Quantifying a Wide Range of Blood Flow Speeds in Live Animals

Overview of attention for article published in PLOS ONE, June 2012
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Title
Line-Scanning Particle Image Velocimetry: An Optical Approach for Quantifying a Wide Range of Blood Flow Speeds in Live Animals
Published in
PLOS ONE, June 2012
DOI 10.1371/journal.pone.0038590
Pubmed ID
Authors

Tyson N. Kim, Patrick W. Goodwill, Yeni Chen, Steven M. Conolly, Chris B. Schaffer, Dorian Liepmann, Rong A. Wang

Abstract

The ability to measure blood velocities is critical for studying vascular development, physiology, and pathology. A key challenge is to quantify a wide range of blood velocities in vessels deep within living specimens with concurrent diffraction-limited resolution imaging of vascular cells. Two-photon laser scanning microscopy (TPLSM) has shown tremendous promise in analyzing blood velocities hundreds of micrometers deep in animals with cellular resolution. However, current analysis of TPLSM-based data is limited to the lower range of blood velocities and is not adequate to study faster velocities in many normal or disease conditions.

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Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Israel 1 1%
Finland 1 1%
Canada 1 1%
Korea, Republic of 1 1%
Unknown 92 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 28%
Researcher 24 25%
Student > Master 13 13%
Student > Doctoral Student 5 5%
Student > Bachelor 4 4%
Other 9 9%
Unknown 15 15%
Readers by discipline Count As %
Engineering 20 21%
Agricultural and Biological Sciences 18 19%
Neuroscience 17 18%
Physics and Astronomy 7 7%
Medicine and Dentistry 6 6%
Other 9 9%
Unknown 20 21%