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Aldosterone Inhibits the Fetal Program and Increases Hypertrophy in the Heart of Hypertensive Mice

Overview of attention for article published in PLOS ONE, May 2012
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Title
Aldosterone Inhibits the Fetal Program and Increases Hypertrophy in the Heart of Hypertensive Mice
Published in
PLOS ONE, May 2012
DOI 10.1371/journal.pone.0038197
Pubmed ID
Authors

Feriel Azibani, Yvan Devaux, Guillaume Coutance, Saskia Schlossarek, Evelyne Polidano, Loubina Fazal, Regine Merval, Lucie Carrier, Alain Cohen Solal, Christos Chatziantoniou, Jean-Marie Launay, Jane-Lise Samuel, Claude Delcayre

Abstract

Arterial hypertension (AH) induces cardiac hypertrophy and reactivation of "fetal" gene expression. In rodent heart, alpha-Myosin Heavy Chain (MyHC) and its micro-RNA miR-208a regulate the expression of beta-MyHC and of its intronic miR-208b. However, the role of aldosterone in these processes remains unclear.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 31%
Researcher 6 19%
Student > Bachelor 4 13%
Student > Doctoral Student 3 9%
Student > Master 3 9%
Other 4 13%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 50%
Biochemistry, Genetics and Molecular Biology 5 16%
Medicine and Dentistry 5 16%
Neuroscience 1 3%
Unknown 5 16%